Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.87 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 4/20 | 0.56 |
| ▸ | PRKACG | P22612 | 4/20 | 0.56 |
| ▸ | PRKACB | P22694 | 4/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980254 | 0.93 | SRC (1.00) | SRCP2RX4LMNAMAPTHTT | |
| SCHEMBL872109 | 0.86 | P2RX4 (0.81) | SRCP2RX4LMNAMAPTHTT | |
| SCHEMBL23161502 | 0.79 | P2RX4 (0.61) | SRCP2RX4LMNAMAPTHTT | |
| SCHEMBL12034344 | 0.79 | P2RX4 (0.61) | SRCP2RX4LMNAMAPTHTT | |
| SCHEMBL7984723 | 0.79 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7981518 | 0.79 | P2RX4 (0.56) | SRCP2RX4LMNAMAPTHTT | |
| SCHEMBL29108116 | 0.78 | LMNA (0.71) | SRCP2RX4LMNAMAPTHTT | |
| SCHEMBL12611492 | 0.78 | P2RX4 (1.00) | SRCP2RX4LMNAMAPTHTT | |
| SCHEMBL12034343 | 0.76 | P2RX4 (0.56) | SRCP2RX4LMNAMAPTHTT | |
| SCHEMBL28810781 | 0.75 | LMNA (0.73) | SRCP2RX4LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |