Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837492 | 0.85 | RAB9A (0.63) | RAB9ANPC1ALOX12KMT2AMEN1 | |
| SCHEMBL904444 | 0.82 | NPC1 (0.60) | RAB9ANPC1KMT2AMEN1MAPK10 | |
| SCHEMBL29408382 | 0.82 | NPC1 (0.60) | RAB9ANPC1KMT2AMEN1MAPK10 | |
| SCHEMBL20520184 | 0.80 | RAB9A (0.43) | RAB9ANPC1ALOX12KMT2AMEN1 | |
| SCHEMBL3842730 | 0.79 | LCK (0.54) | RAB9ANPC1ALOX12KMT2AMEN1 | |
| SCHEMBL25175479 | 0.78 | RAB9A (0.63) | RAB9ANPC1KMT2AMEN1MAPK10 | |
| SCHEMBL15601793 | 0.78 | RAB9A (0.48) | RAB9ANPC1ALOX12KMT2AMEN1 | |
| SCHEMBL29582475 | 0.77 | MEN1 (0.64) | RAB9ANPC1KMT2AMEN1MAPK10 | |
| SCHEMBL626575 | 0.77 | MEN1 (0.64) | RAB9ANPC1KMT2AMEN1MAPK10 | |
| SCHEMBL5750559 | 0.77 | KDR (0.56) | RAB9ANPC1KMT2AMEN1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130253185-A1 | NOVEL CATALYSTS | DALHOUSIE UNIVERSITY (CA) | 2013-09-26 | — | — | US | disclosed |
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |