Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | HTR7 | P34969 | 4/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178433 | 0.91 | HTR6 (0.51) | HTR6HTR1ADRD2HTR7MET | |
| SCHEMBL3176282 | 0.91 | HTR6 (0.51) | HTR6HTR1ADRD2HTR7MET | |
| SCHEMBL3169115 | 0.91 | HTR6 (0.51) | HTR6HTR1ADRD2HTR7MET | |
| SCHEMBL3186106 | 0.81 | HTR6 (0.49) | HTR6HTR1ADRD2HTR7MET | |
| SCHEMBL3182029 | 0.81 | HTR6 (0.49) | HTR6HTR1ADRD2HTR7MET | |
| SCHEMBL3178753 | 0.81 | HTR6 (0.49) | HTR6HTR1ADRD2HTR7MET | |
| SCHEMBL3174816 | 0.81 | HTR6 (0.46) | HTR6METPRKCQ | |
| SCHEMBL3168400 | 0.81 | HTR6 (0.46) | HTR6METPRKCQ | |
| SCHEMBL3178308 | 0.81 | HTR6 (0.46) | HTR6METPRKCQ | |
| SCHEMBL3175968 | 0.80 | HTR6 (0.51) | HTR6HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008832-A1 | PYRROLO-PYRIDINE-3-YL-PIPERAZINE DERIVATIVES HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-21 | — | — | WO | disclosed |