Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981338 | 1.00 | KDM4E (0.56) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL7968441 | 1.00 | KDM4E (0.56) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL38658291 | 0.85 | ALDH1A1 (0.65) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL7968240 | 0.82 | MEN1 (0.43) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL7271109 | 0.82 | MEN1 (0.43) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL31343774 | 0.77 | MEN1 (0.38) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL12715398 | 0.75 | CRBN (0.43) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL7265416 | 0.75 | CES1 (0.40) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL12714533 | 0.75 | CRBN (0.44) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL8404564 | 0.75 | ALDH1A1 (0.67) | KDM4EGAAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |