Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.63 |
| ▸ | ITGAV | P06756 | 20/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969251 | 0.90 | ITGB3 (0.66) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982819 | 0.88 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982241 | 0.86 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL7346966 | 0.84 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982721 | 0.84 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL7979117 | 0.83 | ITGB3 (0.64) | ITGB3ITGAVITGA2B | |
| SCHEMBL7346960 | 0.82 | ITGB3 (0.50) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982407 | 0.81 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL7979126 | 0.78 | ITGB3 (0.45) | ITGB3ITGAVITGA2B | |
| SCHEMBL7979123 | 0.78 | ITGB3 (0.47) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |
| EP-0939757-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | Dupont Pharmaceuticals Company (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1997023480-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |