Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 7/20 | 0.48 |
| ▸ | BRD4 | O60885 | 10/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986958 | 0.88 | LCK (0.44) | LCKBRD4 | |
| SCHEMBL7987020 | 0.88 | LCK (0.44) | LCKBRD4 | |
| SCHEMBL7983073 | 0.85 | LCK (0.57) | LCKBRD4 | |
| SCHEMBL7986998 | 0.83 | LCK (0.48) | LCKBRD4 | |
| SCHEMBL7984150 | 0.83 | LCK (0.47) | LCKBRD4 | |
| SCHEMBL7984171 | 0.81 | LCK (0.44) | LCKBRD4 | |
| SCHEMBL7984167 | 0.81 | LCK (0.44) | LCKBRD4 | |
| SCHEMBL7983009 | 0.80 | LCK (0.53) | LCK | |
| SCHEMBL7981177 | 0.74 | LCK (0.46) | LCK | |
| SCHEMBL7981461 | 0.74 | LCK (0.46) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |