Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 7/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 6/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984171 | 1.00 | LCK (0.44) | LCKFDPSDPP4BRD4PDE4B | |
| SCHEMBL7983073 | 0.88 | LCK (0.57) | LCKBRD4 | |
| SCHEMBL7984150 | 0.86 | LCK (0.47) | LCKBRD4 | |
| SCHEMBL7987020 | 0.85 | LCK (0.44) | LCKBRD4 | |
| SCHEMBL7986958 | 0.85 | LCK (0.44) | LCKBRD4 | |
| SCHEMBL7986998 | 0.83 | LCK (0.48) | LCKBRD4 | |
| SCHEMBL7980656 | 0.81 | LCK (0.48) | LCKBRD4 | |
| SCHEMBL7983009 | 0.77 | LCK (0.53) | LCK | |
| SCHEMBL7981177 | 0.72 | LCK (0.46) | LCK | |
| SCHEMBL7981461 | 0.72 | LCK (0.46) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |