Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980660 | 0.92 | NPC1 (0.68) | KMT2AL3MBTL1HTTNPSR1NPC1 | |
| SCHEMBL7992673 | 0.86 | RAB9A (0.54) | KMT2AL3MBTL1HTTNPSR1NPC1 | |
| SCHEMBL7980669 | 0.83 | NPC1 (0.80) | KMT2AL3MBTL1NPSR1NPC1RAB9A | |
| SCHEMBL7992893 | 0.83 | NPC1 (0.58) | KMT2AL3MBTL1NPSR1NPC1RAB9A | |
| SCHEMBL7994882 | 0.80 | NPC1 (0.80) | KMT2ANPSR1NPC1RAB9ATP53 | |
| SCHEMBL13506223 | 0.80 | SMN1; SMN2 (0.68) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL7991544 | 0.80 | TP53 (0.61) | KMT2AL3MBTL1HTTNPC1RAB9A | |
| SCHEMBL7994876 | 0.80 | NPSR1 (0.69) | KMT2AL3MBTL1NPSR1NPC1RAB9A | |
| SCHEMBL17856292 | 0.79 | NPC1 (0.65) | KMT2AL3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL6037565 | 0.79 | KMT2A (0.59) | KMT2AL3MBTL1HTTNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | claimed |
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | disclosed |