Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980694 | 1.00 | GNRHR (0.63) | GNRHR | |
| SCHEMBL8079137 | 0.88 | GNRHR (0.61) | GNRHR | |
| SCHEMBL7980869 | 0.83 | CACNA1B (0.46) | GNRHR | |
| SCHEMBL8183827 | 0.83 | CACNA1B (0.54) | GNRHR | |
| SCHEMBL8183825 | 0.83 | CACNA1B (0.54) | GNRHR | |
| SCHEMBL7980867 | 0.83 | CACNA1B (0.46) | GNRHR | |
| SCHEMBL7977280 | 0.82 | GNRHR (0.81) | GNRHR | |
| SCHEMBL7977286 | 0.82 | GNRHR (0.81) | GNRHR | |
| SCHEMBL8523631 | 0.80 | GNRHR (0.54) | GNRHR | |
| SCHEMBL8523626 | 0.80 | GNRHR (0.54) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228867-B1 | 2-PHENYL-PYRROLO(2,3-B)PYRIDINE DERIVATIVES FOR TREATING UROGENITAL AND SLEEP DISORDERS; ANTICARCINOGENIC AGENTS; BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-05-08 | — | — | US | disclosed |