SCHEMBL7977280

SCHEMBL7977280

Cc1cc(C)cc(-c2[nH]c3ncc(C(C)(C)C(=O)N4C5CCC4CC5)cc3c2[C@H](C)CNCCCCc2ccncc2)c1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977286 1.00 GNRHR (0.81) GNRHR
SCHEMBL7905285 0.89 GNRHR (1.00) GNRHR
SCHEMBL8088014 0.86 GNRHR (0.80) GNRHR
SCHEMBL8088012 0.86 GNRHR (0.80) GNRHR
SCHEMBL7980694 0.82 GNRHR (0.63) GNRHR
SCHEMBL7980696 0.82 GNRHR (0.63) GNRHR
SCHEMBL8162514 0.80 GNRHR (1.00) GNRHR
SCHEMBL7871273 0.80 GNRHR (1.00) GNRHR
SCHEMBL4362903 0.79 GNRHR (0.73) GNRHR
SCHEMBL13812065 0.79 GNRHR (0.73) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6228867-B1 2-PHENYL-PYRROLO(2,3-B)PYRIDINE DERIVATIVES FOR TREATING UROGENITAL AND SLEEP DISORDERS; ANTICARCINOGENIC AGENTS; BENIGN PROSTATIC HYPERPLASIA MERCK & CO., INC. 2001-05-08 US disclosed