SCHEMBL7980729

SCHEMBL7980729

Cc1ccccc1C(CCC(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.49
MMP9 P14780 2/20 0.49
MMP12 P39900 2/20 0.49
CPA3 P15088 1/20 0.45
CYP1A2 P05177 3/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP2D6 P10635 2/20 0.42
TSHR P16473 2/20 0.42
CYP2C19 P33261 1/20 0.42
GAA P10253 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41
NFKB1 P19838 1/20 0.41
APEX1 P27695 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20564111 0.90 CYSLTR2 (0.46) MMP2MMP9MMP12CPA3CYP1A2
SCHEMBL20563923 0.89 CYSLTR2 (0.42) MMP2MMP9MMP12CPA3CYP1A2
SCHEMBL20564477 0.87 CYSLTR2 (0.44) MMP2MMP9MMP12ALDH1A1MAPK1
SCHEMBL14360149 0.87 CYSLTR2 (0.44) MMP2MMP9MMP12ALDH1A1MAPK1
SCHEMBL20563775 0.87 CYSLTR2 (0.44) MMP2MMP9MMP12ALDH1A1MAPK1
SCHEMBL7007322 0.87 CYSLTR2 (0.44) MMP2MMP9MMP12ALDH1A1MAPK1
SCHEMBL6262528 0.84 ACP3 (0.41) CYP1A2ALDH1A1CYP2D6TSHRCYP2C19
SCHEMBL5156714 0.83 P2RX7 (0.42) CYP1A2ALDH1A1TSHRGAAKDM4E
SCHEMBL10525325 0.82 CYP1A2 (0.57) CYP1A2ALDH1A1TSHRGAAKDM4E
SCHEMBL10976123 0.81 CNR2 (0.42) ALDH1A1POLBCYP3A4MAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113444005-B Method for synthesizing novel glutaric acid compound from diaryl substituted non-activated olefin 四川大学 2023-03-03 CN disclosed
CN-113444005-A Method for synthesizing novel glutaric acid compound from diaryl substituted non-activated olefin 四川大学 2021-09-28 CN disclosed
CN-109641874-A C for target protein degradation3The glutarimide degron body of carbon connection C4医药公司 2019-04-16 CN disclosed
US-6294577-B1 TREATING THE OBJECT OR AREA WITH ANT REPELLENT AGENT SELECTED FROM DIMETHYL SUCCINATE, DIETHYL ADIPATE, DIETHYL MALONATE, AND MIXTURES AND CARRIERS FOR REPELLING ANTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2001-09-25 US disclosed