Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980788 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL6579123 | 0.97 | TP53 (0.46) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL6578709 | 0.97 | TP53 (0.46) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL6579121 | 0.97 | TP53 (0.46) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL6578711 | 0.97 | TP53 (0.46) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL7974960 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL7974963 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL6578893 | 0.94 | TP53 (0.44) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL6578895 | 0.94 | TP53 (0.44) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL6579642 | 0.92 | TP53 (0.42) | MAPTTP53THRBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |