Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982326 | 0.82 | HPRT1 (0.51) | HPRT1KDM4EALDH1A1GAA | |
| SCHEMBL7570074 | 0.82 | HPRT1 (0.53) | HPRT1KDM4EALDH1A1GAALMNA | |
| SCHEMBL7575108 | 0.82 | HPRT1 (0.53) | HPRT1 | |
| SCHEMBL7570874 | 0.82 | HPRT1 (0.45) | HPRT1KDM4EALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7567089 | 0.81 | HPRT1 (0.54) | HPRT1 | |
| SCHEMBL7576799 | 0.80 | HPRT1 (0.51) | HPRT1LMNA | |
| SCHEMBL7570897 | 0.80 | CA1 (0.50) | HPRT1ALDH1A1POLBRXFP1 | |
| SCHEMBL7570987 | 0.80 | MEN1 (0.51) | ALDH1A1CYP2C19LMNATSHR | |
| SCHEMBL7575074 | 0.79 | HPRT1 (0.48) | HPRT1KDM4EALDH1A1CYP2C19GAA | |
| SCHEMBL7570941 | 0.79 | HPRT1 (0.49) | HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297226-B1 | TREATING A DISEASE OR A CONDITION IN A MAMMAL TREATABLE BY INHIBITING THE ACTIVITY OF A MONOAMINE OXIDASE | NEOTHERAPEUTICS, INC. | 2001-10-02 | — | — | US | claimed |
| US-6297226-B1 | TREATING A DISEASE OR A CONDITION IN A MAMMAL TREATABLE BY INHIBITING THE ACTIVITY OF A MONOAMINE OXIDASE | NEOTHERAPEUTICS, INC. | 2001-10-02 | — | — | US | disclosed |