Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.77 |
| ▸ | ITGAV | P06756 | 20/20 | 0.77 |
| ▸ | ITGB5 | P18084 | 9/20 | 0.62 |
| ▸ | ITGB6 | P18564 | 8/20 | 0.62 |
| ▸ | ITGB8 | P26012 | 8/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376995 | 0.91 | ITGB3 (0.86) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL10051022 | 0.87 | ITGAV (0.71) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6262063 | 0.87 | ITGB3 (0.74) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6421618 | 0.87 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL10051072 | 0.86 | ITGAV (0.68) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL21706071 | 0.86 | ITGB3 (0.90) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL22029444 | 0.86 | ITGB3 (0.90) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| Hydrochloric Acid SCHEMBL6424214 | 0.86 | ITGB3 (0.72) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| Hydrochloric Acid SCHEMBL29416400 | 0.86 | ITGB3 (0.72) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6266479 | 0.85 | ITGAV (0.67) | ITGB3ITGAVITGB5ITGB6ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294549-B1 | COMPOUNDS USEFUL FOR INHIBITING RESTENOSIS, ANGIOGENESIS, ATHEROSCLEROSIS, DIABETIC RETINOPATHY, MACULAR DEGENERATION, INFLAMMATION OR TUMOR GROWTH. | MERCK & CO., INC. | 2001-09-25 | — | — | US | disclosed |
| US-5952306-A | INHIBITING THE BINDING OF FIBRINOGEN TO BLOOD PLATELETS AND INHIBITING THE AGGREGATION OF BLOOD PLATELETS; INHIBITING OSTEOCLAST CELLULAR ADHESION TO BONE SURFACES | MERCK & CO., INC. (US) | 1999-09-14 | — | — | US | disclosed |