Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.80 |
| ▸ | HTR1D | P28221 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985977 | 0.99 | HTR1A (0.79) | HTR1AHTR1DMAPTTHRBALDH1A1 | |
| SCHEMBL7988761 | 0.96 | HTR1A (0.74) | HTR1AHTR1DMAPTTHRBALDH1A1 | |
| SCHEMBL7988547 | 0.90 | HTR1A (0.81) | HTR1AHTR1DMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6598470 | 0.89 | HTR1A (0.79) | HTR1AHTR1DMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL7983291 | 0.89 | HTR1A (0.80) | HTR1AHTR1DMAPTALDH1A1HTT | |
| SCHEMBL6597325 | 0.88 | HTR1A (1.00) | HTR1AHTR1DMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6598515 | 0.88 | HTR1A (0.78) | HTR1AHTR1DMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6598512 | 0.88 | HTR1A (0.98) | HTR1AHTR1DMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6598609 | 0.85 | HTR1A (0.73) | HTR1AHTR1DMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6600035 | 0.81 | HTR1A (0.98) | HTR1AHTR1DMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262056-B1 | TREATING ANXIETY OR DEPRESSION | VITA-INVEST, SA (ES) | 2001-07-17 | — | — | US | disclosed |