Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981099 | 1.00 | ADRB3 (0.45) | ADRB3ADRA1AMAOBTDP1ADRB2 | |
| SCHEMBL7979311 | 0.93 | ADRB3 (0.42) | ADRB3ADRA1AMAOBTDP1ADRB2 | |
| SCHEMBL7979314 | 0.93 | ADRB3 (0.42) | ADRB3ADRA1AMAOBTDP1ADRB2 | |
| SCHEMBL7107952 | 0.89 | ADRB3 (0.48) | ADRB3ADRA1A | |
| SCHEMBL7967366 | 0.86 | ADRB3 (0.47) | ADRB3ADRA1AADRB2 | |
| SCHEMBL7967364 | 0.86 | ADRB3 (0.55) | ADRB3ADRA1A | |
| SCHEMBL7967369 | 0.86 | ADRB3 (0.55) | ADRB3ADRA1A | |
| SCHEMBL7980858 | 0.86 | ADRB3 (0.55) | ADRB3ADRA1A | |
| Hydrochloric Acid SCHEMBL7978869 | 0.85 | ADRB3 (0.47) | ADRB3ADRA1AADRB2 | |
| Hydrochloric Acid SCHEMBL7978873 | 0.85 | ADRB3 (0.47) | ADRB3ADRA1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |