Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384952 | 0.72 | NPC1 (0.61) | ALDH1A1RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL27885831 | 0.71 | POLB (0.47) | ALDH1A1RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL24317555 | 0.70 | NPC1 (0.59) | ALDH1A1RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL17948203 | 0.68 | NPC1 (0.57) | ALDH1A1RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL6404441 | 0.68 | ALPL (0.53) | RECQLALDH1A1RAB9ANPC1POLB | |
| SCHEMBL145447 | 0.68 | CHEK1 (0.42) | RECQLALDH1A1RAB9ANPC1POLB | |
| SCHEMBL11218038 | 0.68 | NPC1 (0.45) | RECQLALDH1A1RAB9ANPC1POLB | |
| SCHEMBL7999024 | 0.68 | ALPL (0.53) | RECQLALDH1A1RAB9ANPC1ALPL | |
| Naphthalene SCHEMBL28228080 | 0.66 | NPC1 (0.55) | ALDH1A1RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL11983462 | 0.66 | NPC1 (0.50) | ALDH1A1RAB9ANPC1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297385-B1 | EXHIBIT BOTH THE GOOD COUPLING KINETICS WHICH ARE REQUIRED FOR USE IN PHOTOGRAPHIC FILM MATERIALS, PARTICULARLY COLOR NEGATIVE FILM, AND ALSO AT THE SAME TIME EXHIBIT GOOD DARK FADING STABILITY, EXHIBIT A LOW HALF-BAND WIDTH. | AGFA-GEVAERT (BE) | 2001-10-02 | — | — | US | disclosed |