Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043267 | 0.85 | RAB9A (0.55) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14911778 | 0.82 | PDE10A (0.59) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9971243 | 0.82 | PDE10A (0.59) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7834962 | 0.82 | PDE10A (0.59) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2732396 | 0.82 | PDE10A (0.59) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL9444303 | 0.81 | PDE10A (0.57) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL948504 | 0.81 | PDE10A (0.57) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL12478474 | 0.81 | PDE10A (0.57) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14974190 | 0.79 | PDE10A (0.56) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7507665 | 0.79 | PDE10A (0.56) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174877-B1 | EXCELLANT BACTERICIDES, ORAL ABSORBABILITY AND STABILITY; IMPROVE THE STABILITY TO RENAL DEHYDROPEPTIDASE I (DHP-I); 2-(2-(N-HETEROCYCLIC-ETHYLTHIO-) DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0876370-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025325-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |