Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032628 | 0.93 | SCN8A (0.57) | SCN8AMEN1KMT2ACHRM2KDM4E | |
| SCHEMBL4242842 | 0.88 | SCN8A (0.57) | SCN8AMEN1KMT2AKDM4EDPP7 | |
| SCHEMBL4238709 | 0.84 | SCN8A (0.64) | SCN8AMEN1KMT2ACHRM2KDM4E | |
| SCHEMBL8609568 | 0.82 | SCN8A (0.56) | SCN8AMEN1KMT2ACHRM2KDM4E | |
| SCHEMBL3508827 | 0.82 | SIGMAR1 (0.63) | SCN8AMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL4235847 | 0.82 | SCN8A (0.65) | SCN8AMEN1KMT2AKDM4EDPP7 | |
| SCHEMBL10873718 | 0.82 | SCN8A (0.61) | SCN8AMEN1KMT2ACHRM2KDM4E | |
| SCHEMBL7249965 | 0.81 | TAAR1 (0.62) | SCN8AMEN1KMT2AKDM4EDPP7 | |
| SCHEMBL4239980 | 0.81 | DPP7 (0.59) | SCN8AMEN1KMT2AKDM4EDPP7 | |
| SCHEMBL1047618 | 0.80 | TAAR1 (0.59) | MEN1KMT2AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214833-B1 | MADE BY ACYLATION | ZAMBON GROUP S.P.A. (IT) | 2001-04-10 | — | — | US | disclosed |
| EP-0970075-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998043972-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1998-10-08 | — | — | WO | disclosed |