SCHEMBL7981865

SCHEMBL7981865

ClCc1c(Cl)nc(Cl)nc1Cl

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71862 0.82 ALDH1A1 (0.32) ALDH1A1ALOX15TSHR
SCHEMBL30891068 0.82 ALDH1A1 (0.32) ALDH1A1ALOX15TSHR
SCHEMBL11564388 0.80 KMT2A (0.41) ALDH1A1
SCHEMBL11553510 0.78
SCHEMBL29451086 0.77 CYP1A2 (0.48) ALDH1A1
SCHEMBL22139826 0.77 CYP1A2 (0.48) ALDH1A1
SCHEMBL17974142 0.73 ALDH1A1 (0.39) ALDH1A1ALOX15TSHR
SCHEMBL31261883 0.73 ALDH1A1 (0.39) ALDH1A1ALOX15TSHR
SCHEMBL501823 0.73 ALDH1A1 (0.39) ALDH1A1ALOX15TSHR
SCHEMBL12481167 0.73 ALDH1A1 (0.39) ALDH1A1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574134-A Preparation method of treasipril and salt thereof 济南圣泉集团股份有限公司 2026-02-27 CN disclosed
US-6297374-B1 Nitroimino-nitromethylene—azole or-azine heterocyclic compounds, insecticidal compositions containing them, and insecticidal methods of using them NIHON BAYER AGROCHEM K.K. (JP) 2001-10-02 US disclosed
US-6022967-A 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES NIHON BAYER AGROCHEM K.K. (JP) 2000-02-08 US disclosed
US-5750704-A INSECTICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-05-12 US disclosed
US-5580889-A Insecticidal nitromethyl or niteoimino-heteromethyl-heterocyclics NIHON BAYER AGROCHEM K.K. (JP) 1996-12-03 US disclosed
US-5461167-A 2-chloro-5-chloromethyl thiazole; insecticide NIHON BAYER AGROCHEM K.K. (JP) 1995-10-24 US disclosed
US-5428032-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1995-06-27 US disclosed
US-5298507-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1994-03-29 US disclosed
US-5204360-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1993-04-20 US disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0114575-B1 2,4-DIAMINO-6-HALOGEN-5-TRIFLUOROMETHYL PYRIMIDINE WITH HERBICIDAL ACTIVITY CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed
US-4507146-A PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1985-03-26 US disclosed
EP-0114575-A1 2,4-Diamino-6-halogen-5-trifluoromethyl pyrimidine with herbicidal activity CIBA-GEIGY AG (CH) 1984-08-01 EP disclosed
US-4137412-A REACTING HALOGENO-AZAALKENE WITH ALPHA, BETA-UNSATURATED NITRILE BAYER AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed
US-4137252-A FREE RADICAL POLYMERIZATION CATALYST, CURING CATALYST NIPPON OIL AND FATS CO., LTD. (JP) 1979-01-30 US disclosed