Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 4/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260037 | 0.78 | KDM4E (0.40) | BRD4KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL12305011 | 0.72 | KDM4E (0.45) | BRD4KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL12603538 | 0.69 | CSF1R (0.43) | BRD4KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL25407739 | 0.67 | KDM4E (0.34) | BRD4KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL7338617 | 0.67 | BRD4 (0.36) | BRD4TDO2HCAR2 | |
| SCHEMBL19367734 | 0.67 | BRD4 (0.72) | BRD4TDO2KDM4EJAK2BRD2 | |
| SCHEMBL544899 | 0.67 | BRD4 (1.00) | BRD4TDO2BRD2 | |
| SCHEMBL12305013 | 0.66 | CSF1R (0.40) | BRD4KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL7981965 | 0.66 | MAPT (0.37) | BRD4KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL10519198 | 0.65 | NPC1 (0.56) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000229955-A | 5-AMINOISOXAZOLYLISOXAZOLE AND ITS PRODUCTION | NIPPON SODA CO LTD | 2000-08-22 | — | — | JP | disclosed |
| JP-2000229954-A | 3-METHYL-5-[(CIS)-1-PROPENYL]ISOXAZOLE AND ITS PRODUCTION | NIPPON SODA CO LTD | 2000-08-22 | — | — | JP | disclosed |