Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | TLR4 | O00206 | 1/20 | 0.61 |
| ▸ | TLR2 | O60603 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | BCR | P11274 | 1/20 | 0.61 |
| ▸ | PRKCA | P17252 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841808 | 0.88 | MAPT (0.68) | ROCK1KMT2AMEN1TLR4TLR2 | |
| SCHEMBL3662059 | 0.84 | ROCK1 (0.65) | ROCK1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL3889079 | 0.83 | MEN1 (0.62) | ROCK1KMT2AMEN1TLR4TLR2 | |
| SCHEMBL2285411 | 0.83 | ABL1 (0.69) | ROCK1KMT2AMEN1TLR4TLR2 | |
| SCHEMBL12486025 | 0.81 | ROCK1 (0.62) | ROCK1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL394734 | 0.80 | KMT2A (0.67) | ROCK1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL2717131 | 0.79 | HPGD (0.69) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL1539911 | 0.78 | KMT2A (0.60) | ROCK1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL25371875 | 0.78 | KMT2A (0.60) | ROCK1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL5484658 | 0.78 | ABCG2 (0.72) | ROCK1KMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074769-A | Compositions and methods for treating proliferative disorders | 艾科尔公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-103748093-B | Imidazopyridyl-the aminopyridine compounds being replaced | ARQULE, INC. (US) | 2016-06-01 | — | — | CN | disclosed |
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |