Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841808 | 0.85 | MAPT (0.68) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL7982040 | 0.83 | ROCK1 (0.63) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL913419 | 0.82 | MEN1 (0.69) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL15960021 | 0.81 | MEN1 (0.68) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL4583278 | 0.81 | HPGD (0.61) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL27827795 | 0.77 | MEN1 (0.71) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL913813 | 0.77 | MEN1 (1.00) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL2407197 | 0.76 | L3MBTL1 (0.66) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL5204557 | 0.76 | CXCR4 (0.70) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL9479463 | 0.76 | ALOX12 (1.00) | MEN1KMT2AMAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329288-B2 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2008-02-12 | — | — | US | claimed |
| US-20060005323-A1 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | claimed |
| EP-1568694-A1 | N-heteroaryl-para-phenylene diamines for colouring hair | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-8486962-B2 | N-(2-Methoxy-phenyl)-2-oxo-2-(2-phenyl-indolizin-3-yl)-acetamide; antifungal agents; inhibiting Aspergillus | F2G LTD. (GB) | 2013-07-16 | — | — | US | disclosed |
| EP-1888063-B1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-01-14 | — | — | EP | disclosed |
| US-20080161302-A1 | N-(2-Methoxy-phenyl)-2-oxo-2-(2-phenyl-indolizin-3-yl)-acetamide; antifungal agents; inhibiting Aspergillus | F2G LTD. (GB) | 2008-07-03 | — | — | US | disclosed |
| EP-1888063-A1 | ANTIFUNGAL AGENTS | F2G Ltd. (GB) | 2008-02-20 | — | — | EP | disclosed |
| US-7329288-B2 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2008-02-12 | — | — | US | disclosed |
| US-7329288-B2 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2008-02-12 | — | — | US | disclosed |
| WO-2006123145-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2006-11-23 | — | — | WO | disclosed |
| US-20060005323-A1 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
| EP-1568694-A1 | N-heteroaryl-para-phenylene diamines for colouring hair | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
| EP-1568694-A1 | N-heteroaryl-para-phenylene diamines for colouring hair | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161302-A1 | N-(2-Methoxy-phenyl)-2-oxo-2-(2-phenyl-indolizin-3-yl)-acetamide; antifungal agents; inhibiting Aspergillus | NAT1, CYP1A2, CYP51A1 | MEN1 325/4885KMT2A 603/4885MAPT 2792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.