Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3161752 | 0.99 | KMT2A (0.52) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL3161761 | 0.99 | KMT2A (0.52) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2566894 | 0.93 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2122570 | 0.93 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL30737943 | 0.93 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL23252189 | 0.93 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2566892 | 0.93 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2122565 | 0.93 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2569950 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2569954 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169106-B1 | ANTITUMOUR AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-01-02 | — | — | US | disclosed |