Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL741752 | 0.84 | NPSR1 (0.64) | NPSR1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL7982484 | 0.84 | HTT (0.49) | NPSR1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL8044893 | 0.82 | NPSR1 (0.61) | NPSR1KMT2ATSHRMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL8550497 | 0.82 | NPSR1 (0.61) | NPSR1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL3430030 | 0.81 | NPSR1 (0.47) | NPSR1KMT2ATSHRNPC1ATR | |
| SCHEMBL19031886 | 0.81 | NPSR1 (0.49) | NPSR1KMT2ATSHRNPC1ATR | |
| SCHEMBL1471487 | 0.76 | NPSR1 (0.54) | NPSR1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL3426753 | 0.76 | MEN1 (0.54) | NPSR1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL6259046 | 0.76 | HTT (0.50) | NPSR1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL5540103 | 0.75 | NPSR1 (0.52) | NPSR1KMT2ATSHRMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1252068-A | 3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions containing the same | JAPAN TOBACCO INC (JP) | 2000-05-03 | — | — | CN | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |