Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GGT1 | P19440 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28843221 | 1.00 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL3716464 | 0.88 | ALDH1A1 (0.67) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL25788052 | 0.88 | ALDH1A1 (0.67) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL4602778 | 0.88 | ALDH1A1 (0.67) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL8425121 | 0.88 | ALDH1A1 (0.67) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL13609852 | 0.87 | IRAK4 (0.50) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL1899339 | 0.87 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL8441412 | 0.86 | CCNB2 (0.56) | KDM4EKMT2AMEN1RECQLIRAK4 | |
| SCHEMBL29639528 | 0.86 | IRAK4 (0.66) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL29639517 | 0.86 | IRAK4 (0.66) | KDM4EKMT2AMEN1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114921391-A | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| US-6278028-B1 | FOR ELECTROCLINIC DEVICE | THE SECRETARY OF STATE FOR IN DEFENCE IN HER BRITTANIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2001-08-21 | — | — | US | disclosed |