Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988149 | 0.88 | ALDH1A1 (0.48) | ALDH1A1LMNAGAAOPRM1OPRD1 | |
| SCHEMBL6993631 | 0.85 | KCNH2 (0.47) | ALDH1A1LMNAGAAOPRM1OPRD1 | |
| SCHEMBL5007368 | 0.84 | ALDH1A1 (0.53) | ALDH1A1LMNAGAAOPRM1OPRD1 | |
| SCHEMBL3876509 | 0.82 | SMN1; SMN2 (0.50) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL7988314 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL7984810 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL6997081 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LMNAGAAOPRM1OPRD1 | |
| SCHEMBL5125428 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNAGAAOPRM1OPRD1 | |
| SCHEMBL3870704 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAGAAOPRM1OPRD1 | |
| SCHEMBL7623102 | 0.79 | ALDH1A1 (0.52) | ALDH1A1OPRM1OPRD1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211199-B1 | HISTAMINE AND TACHYKININ RECEPTOR ANTAGONISTS; ANTIASTHMATICS, ANTIEMETICS; RESPIRATORY SYSTEM DISORDERS, INFLAMMATORY BOWEL DISEASE, CONJUNCTIVITIS | AVENTIS PHARMACEUTICALS INC. | 2001-04-03 | — | — | US | disclosed |