Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982368 | 0.98 | REN (0.53) | RENHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7986481 | 0.98 | REN (0.53) | RENHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7983610 | 0.98 | REN (0.53) | RENHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7982499 | 0.98 | REN (0.53) | RENHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7972070 | 0.98 | REN (0.53) | RENHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7972013 | 0.96 | REN (0.54) | RENHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7986648 | 0.96 | REN (0.54) | RENHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7983340 | 0.90 | HDAC1 (0.53) | RENHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7973240 | 0.90 | HDAC1 (0.53) | RENHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7202274 | 0.89 | CCR6 (0.56) | RENHDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214833-B1 | MADE BY ACYLATION | ZAMBON GROUP S.P.A. (IT) | 2001-04-10 | — | — | US | disclosed |
| EP-0970075-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998043972-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1998-10-08 | — | — | WO | disclosed |