Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PTPRC | P08575 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962030 | 0.90 | ALDH1A1 (0.63) | ALDH1A1PTPRCS100A4BCHEACHE | |
| SCHEMBL31268201 | 0.90 | ALDH1A1 (0.63) | ALDH1A1PTPRCS100A4BCHEACHE | |
| SCHEMBL4960637 | 0.82 | ALDH1A1 (0.61) | ALDH1A1PTPRCS100A4BCHEACHE | |
| SCHEMBL7985009 | 0.78 | MAPT (0.56) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL7985135 | 0.75 | TYMS (0.48) | ALDH1A1CYP1A2HIF1AHSD17B10CYP3A4 | |
| SCHEMBL158311 | 0.74 | ALDH1A1 (1.00) | ALDH1A1PTPRCS100A4BCHEACHE | |
| SCHEMBL29661178 | 0.74 | ALDH1A1 (1.00) | ALDH1A1PTPRCS100A4BCHEACHE | |
| SCHEMBL9077614 | 0.74 | ALDH1A1 (0.54) | ALDH1A1PTPRCS100A4BCHEACHE | |
| SCHEMBL31268251 | 0.73 | ALDH1A1 (0.71) | ALDH1A1PTPRCS100A4BCHEACHE | |
| SCHEMBL7971442 | 0.72 | KDM4E (0.44) | ALDH1A1HSD17B10TYMSMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300340-B1 | USEFUL FOR THERAPY OF CANCER AND SOLID TUMORS | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| US-6162822-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 2000-12-19 | — | — | US | disclosed |
| EP-0820985-B1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-08-30 | — | — | EP | disclosed |
| EP-0820985-A1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-01-28 | — | — | EP | disclosed |