Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814875 | 0.88 | POLB (0.55) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL7676258 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL7676269 | 0.73 | MAPT (0.60) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL7673938 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL6815989 | 0.71 | MAPT (0.64) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL6811901 | 0.71 | MAPT (0.64) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL6816432 | 0.70 | MAPT (0.60) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL6819964 | 0.70 | MAPT (0.63) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL6815470 | 0.70 | MAPT (0.71) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL6816472 | 0.70 | MAPT (0.68) | ALDH1A1MAPTGAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271236-B1 | PHENYL UREAS/THIOUREAS AS INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE ENZYME, USEFUL IN TREATING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, AND VARICELLA-ZOSTER VIRUS | WYETH | 2001-08-07 | — | — | US | disclosed |