Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 10/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580140 | 0.76 | SLC6A7 (0.80) | SLC6A7SLC6A3 | |
| SCHEMBL13149359 | 0.74 | SLC6A7 (0.92) | SLC6A7SLC6A3HSD17B10L3MBTL1 | |
| SCHEMBL4635518 | 0.73 | HSD17B10 (0.52) | HSD17B10GLAMAPTMGLLPOLB | |
| SCHEMBL3583123 | 0.71 | SLC6A7 (1.00) | SLC6A7SLC6A3HSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4557356 | 0.71 | SLC6A7 (0.62) | SLC6A7SLC6A3HSP90AB1HSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4557354 | 0.71 | SLC6A7 (0.62) | SLC6A7SLC6A3HSP90AB1HSD17B10L3MBTL1 | |
| SCHEMBL30937177 | 0.71 | HSD17B10 (0.56) | HSD17B10GLAMAPTMGLLPOLB | |
| SCHEMBL3575529 | 0.69 | SLC6A7 (1.00) | SLC6A7SLC6A3 | |
| SCHEMBL1258349 | 0.69 | SLC6A7 (0.63) | SLC6A7SLC6A3HSD17B10L3MBTL1 | |
| SCHEMBL6371742 | 0.69 | SLC6A7 (0.63) | SLC6A7SLC6A3HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616077-A1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035423-A1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2012-03-22 | — | — | WO | disclosed |