Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | JAK1 | P23458 | 1/20 | 0.59 |
| ▸ | TYK2 | P29597 | 1/20 | 0.59 |
| ▸ | JAK3 | P52333 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004385 | 0.81 | EGFR (0.71) | MAPK10NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL1518631 | 0.81 | MAPK10 (1.00) | MAPK10NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL29501509 | 0.81 | EGFR (0.61) | MAPK10NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3642226 | 0.81 | MAPK10 (0.51) | MAPK10NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3279571 | 0.80 | MEN1 (1.00) | MAPK10NPC1RAB9AALDH1A1GAA | |
| SCHEMBL30968559 | 0.79 | MAPK10 (0.61) | MAPK10NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL30968557 | 0.79 | MAPK10 (0.61) | MAPK10NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL22470327 | 0.79 | MAPK10 (0.61) | MAPK10NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL22470339 | 0.79 | MAPK10 (0.61) | MAPK10NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL13689760 | 0.78 | KMT2A (0.66) | MAPK10NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |