SCHEMBL3279571

SCHEMBL3279571

c1ccc(Nc2ccccc2Nc2ccccn2)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
MAPK10 P53779 1/20 1.00
GFER P55789 1/20 1.00
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
ADRA2A P08913 2/20 0.50
ADRA2B P18089 2/20 0.50
ADRA2C P18825 2/20 0.50
PKM P14618 1/20 0.50
KDR P35968 4/20 0.48
CXCR4 P61073 1/20 0.48
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
FABP1 P07148 1/20 0.47
FABP6 P51161 1/20 0.47
GAA P10253 1/20 0.47
GRM5 P41594 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3267194 0.89 MEN1 (0.80) MEN1KMT2AMAPK10GFERNPC1
SCHEMBL3265735 0.89 MEN1 (0.80) MEN1KMT2AMAPK10GFERNPC1
SCHEMBL29391624 0.87 KMT2A (0.76) MEN1KMT2AMAPK10GFERNPC1
SCHEMBL221242 0.87 KMT2A (0.76) MEN1KMT2AMAPK10GFERNPC1
SCHEMBL30167997 0.87 MEN1 (0.76) MEN1KMT2AMAPK10GFERNPC1
SCHEMBL3265731 0.87 MEN1 (0.76) MEN1KMT2AMAPK10GFERNPC1
SCHEMBL31220877 0.85 MAPK10 (0.73) MEN1KMT2AMAPK10GFERNPC1
SCHEMBL2485883 0.85 KMT2A (0.73) MEN1KMT2AMAPK10GFERNPC1
SCHEMBL1855727 0.85 MEN1 (0.73) MEN1KMT2AMAPK10GFERNPC1
SCHEMBL29796528 0.85 MAPK10 (0.73) MEN1KMT2AMAPK10GFERRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001895-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-01-01 US disclosed
US-12234251-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-02-25 US disclosed
US-20210292343-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-09-23 US disclosed
US-9074128-B2 Metal complexes having azaborol ligands and electronic device having the same MERCK PATENT GMBH (DE) 2015-07-07 US disclosed
US-8722898-B2 2014-05-13 US disclosed
US-20120004407-A1 METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME MERCK PATENT GMBH (DE) 2012-01-05 US disclosed
WO-2010099852-A1 METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME MERCK PATENT GMBH (DE) 2010-09-10 WO disclosed
US-20060058178-A1 Aromatic compounds containing nitrogen and p- functionalized amines, the production thereof and their use in catalytic reactions DEGUSSA AG (DE) 2006-03-16 US disclosed
EP-1446224-B1 AROMATIC COMPOUNDS CONTAINING NITROGEN AND P-FUNCTIONALIZED AMINES, THE PRODUCTION THEREOF AND THEIR USE IN CATALYTIC REACTIONS DEGUSSA (DE) 2006-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292343-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, NCL MEN1 828/4885KMT2A 3417/4885MAPK10 1357/4885
US-20060058178-A1 Aromatic compounds containing nitrogen and p- functionalized amines, the production thereof and their use in catalytic reactions PAH, PNMT, TYR MEN1 3253/4885KMT2A 943/4885MAPK10 3345/4885
US-20120004407-A1 METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME ICOSLG, ERAL1, CTCF MEN1 1147/4885KMT2A 1795/4885MAPK10 3511/4885
US-20260001895-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NES, NCLN, NR4A1 MEN1 2522/4885KMT2A 2879/4885MAPK10 1747/4885
US-12234251-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, NCL MEN1 828/4885KMT2A 3417/4885MAPK10 1357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.