Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 20/20 | 0.68 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.47 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982574 | 1.00 | FKBP1A (0.68) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7251345 | 0.83 | FKBP1A (0.88) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7252741 | 0.82 | FKBP1A (0.73) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7252100 | 0.82 | FKBP1A (0.73) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7246218 | 0.82 | FKBP1A (0.73) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7976989 | 0.82 | FKBP1A (0.71) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7400429 | 0.81 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL7976724 | 0.81 | FKBP1A (0.64) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7978726 | 0.80 | FKBP1A (0.64) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7978725 | 0.80 | FKBP1A (0.64) | FKBP1AMTORFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323215-B1 | TREAT AND PREVENT DISORDERS CHARACTERIZED BY NEURONAL DAMAGE SUCH AS PARKINSON'S DISEASE, ALZHEIMER'S DISEASE, STROKE, MULTIPLE SCLEROSIS, AMYOTROPHIC LATERAL SCLEROSIS, DIABETIC NEUROPATHY AND BELL'S PALSY. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-11-27 | — | — | US | disclosed |