Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 4/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982797 | 1.00 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19IDO1CYP11B1 | |
| SCHEMBL7833077 | 0.90 | POLB (0.43) | POLBHPGDHTTSMN1; SMN2CHRNA7 | |
| SCHEMBL7966693 | 0.90 | POLB (0.43) | POLBHPGDHTTSMN1; SMN2CHRNA7 | |
| SCHEMBL7833084 | 0.90 | POLB (0.43) | POLBHPGDHTTSMN1; SMN2CHRNA7 | |
| SCHEMBL7836118 | 0.90 | POLB (0.43) | POLBHPGDHTTSMN1; SMN2CHRNA7 | |
| SCHEMBL7979920 | 0.90 | POLB (0.43) | POLBHPGDHTTSMN1; SMN2CHRNA7 | |
| SCHEMBL7836121 | 0.90 | POLB (0.43) | POLBHPGDHTTSMN1; SMN2CHRNA7 | |
| SCHEMBL7834569 | 0.90 | POLB (0.43) | POLBHPGDHTTSMN1; SMN2CHRNA7 | |
| SCHEMBL7964059 | 0.82 | CYP3A4 (0.52) | CYP1A2CYP3A4CYP2C19IDO1CYP11B1 | |
| SCHEMBL7963443 | 0.82 | CYP3A4 (0.52) | CYP1A2CYP3A4CYP2C19IDO1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |