Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205287 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HPGDMCOLN3CRHBPCRHR2 | |
| SCHEMBL3572313 | 0.96 | ALDH1A1 (0.42) | ALDH1A1HPGDMCOLN3CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL30314584 | 0.94 | ALDH1A1 (0.41) | ALDH1A1HPGDMCOLN3CRHBPCRHR2 | |
| SCHEMBL3516822 | 0.86 | ALDH1A1 (0.45) | ALDH1A1HPGDMCOLN3CRHBPCRHR2 | |
| SCHEMBL11472496 | 0.81 | MEN1 (0.45) | THRBMEN1KMT2ASMN1; SMN2SLC18A3 | |
| SCHEMBL20096012 | 0.81 | MEN1 (0.45) | THRBMEN1KMT2ASMN1; SMN2SLC18A3 | |
| SCHEMBL6909004 | 0.81 | MEN1 (0.45) | THRBMEN1KMT2ASMN1; SMN2SLC18A3 | |
| SCHEMBL7343176 | 0.81 | MEN1 (0.45) | THRBMEN1KMT2ASMN1; SMN2SLC18A3 | |
| SCHEMBL14393808 | 0.81 | MEN1 (0.45) | THRBMEN1KMT2ASMN1; SMN2SLC18A3 | |
| SCHEMBL495718 | 0.81 | MEN1 (0.45) | THRBMEN1KMT2ASMN1; SMN2SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |