Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 9/20 | 0.68 |
| ▸ | SELE | P16581 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993959 | 1.00 | SELP (0.68) | SELPSELEMEN1KMT2APTPN1 | |
| SCHEMBL8194916 | 0.92 | SELP (0.58) | SELPSELEMEN1KMT2APTPN1 | |
| SCHEMBL8194911 | 0.92 | SELP (0.58) | SELPSELEMEN1KMT2APTPN1 | |
| SCHEMBL7994592 | 0.89 | SELP (0.56) | SELPSELEMEN1KMT2AEGFR | |
| SCHEMBL7994596 | 0.89 | SELP (0.56) | SELPSELEMEN1KMT2AEGFR | |
| SCHEMBL8181836 | 0.88 | SELP (0.74) | SELPSELEPTPN1EGFR | |
| SCHEMBL7995190 | 0.88 | SELP (0.57) | SELPSELEMEN1KMT2AEGFR | |
| SCHEMBL7999875 | 0.87 | SELP (0.70) | SELPSELEMEN1KMT2APTPN1 | |
| SCHEMBL7999883 | 0.87 | SELP (0.70) | SELPSELEMEN1KMT2APTPN1 | |
| SCHEMBL7999878 | 0.87 | SELP (0.70) | SELPSELEMEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | claimed |
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2000033836-A1 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |