Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 9/20 | 0.70 |
| ▸ | SELE | P16581 | 2/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999883 | 1.00 | SELP (0.70) | SELPSELEPTPN1EGFRP2RY12 | |
| SCHEMBL7999875 | 1.00 | SELP (0.70) | SELPSELEPTPN1EGFRP2RY12 | |
| SCHEMBL8000163 | 0.91 | SELP (0.59) | SELPSELEPTPN1EGFRP2RY12 | |
| SCHEMBL8215649 | 0.91 | SELP (0.59) | SELPSELEPTPN1EGFRP2RY12 | |
| SCHEMBL8000157 | 0.91 | SELP (0.59) | SELPSELEPTPN1EGFRP2RY12 | |
| SCHEMBL8194911 | 0.90 | SELP (0.58) | SELPSELEPTPN1EGFRP2RY12 | |
| SCHEMBL8194916 | 0.90 | SELP (0.58) | SELPSELEPTPN1EGFRP2RY12 | |
| SCHEMBL8181836 | 0.90 | SELP (0.74) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL7993959 | 0.87 | SELP (0.68) | SELPSELEPTPN1EGFRADORA3 | |
| SCHEMBL7982779 | 0.87 | SELP (0.68) | SELPSELEPTPN1EGFRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2000033836-A1 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |