Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982889 | 0.82 | HDAC1 (0.45) | KDM1AMEN1KMT2AATMCHEK2 | |
| SCHEMBL7984274 | 0.81 | KDM4E (0.53) | KDM4E | |
| SCHEMBL13086758 | 0.79 | MEN1 (0.50) | MEN1KMT2AOPRD1 | |
| SCHEMBL6612547 | 0.77 | NPC1 (0.57) | KDM1AALDH1A1ATMHCRTR2PRMT5 | |
| SCHEMBL31480370 | 0.76 | MEN1 (0.48) | KDM1AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13086595 | 0.76 | MEN1 (0.49) | MEN1KMT2AOPRD1 | |
| SCHEMBL8703344 | 0.75 | MEN1 (0.45) | KDM1AMEN1KMT2ATP53HCRTR2 | |
| SCHEMBL702497 | 0.75 | ATM (0.43) | KDM1AOPRD1ATMCHEK2HPGD | |
| SCHEMBL13086597 | 0.75 | MEN1 (0.48) | MEN1KMT2AOPRD1 | |
| SCHEMBL6012084 | 0.75 | MEN1 (0.48) | MEN1KMT2AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |