Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.49 |
| ▸ | EED | O75530 | 1/20 | 0.48 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.48 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.48 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.48 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058311 | 0.88 | KDM4E (0.56) | KDM4EPKMGPR119EEDRBBP4 | |
| SCHEMBL4151572 | 0.84 | TGFBR1 (0.53) | KDM4EPKMGPR119FAAHTGFBR1 | |
| SCHEMBL8233089 | 0.84 | KDM4E (0.54) | KDM4EPKMGPR119STSFAAH | |
| SCHEMBL7982886 | 0.81 | KDM1A (0.45) | KDM4E | |
| SCHEMBL4144200 | 0.80 | GPR119 (0.51) | KDM4EPKMGPR119FAAH | |
| SCHEMBL13913655 | 0.80 | KDM4E (0.60) | KDM4EPKMGPR119STSFAAH | |
| SCHEMBL7495311 | 0.80 | GPR119 (0.53) | KDM4EPKMGPR119FAAH | |
| SCHEMBL4152000 | 0.80 | KDM4E (0.49) | KDM4EPKMGPR119FAAHTGFBR1 | |
| SCHEMBL1475361 | 0.79 | KDM4E (0.54) | KDM4EPKMGPR119EEDRBBP4 | |
| SCHEMBL15629521 | 0.79 | HTR2A (0.49) | KDM4EPKMGPR119EEDRBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |