Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752332 | 0.81 | SMN1; SMN2 (0.31) | SMN1; SMN2ADH1BADH1CADH1ATSHR | |
| SCHEMBL10752328 | 0.81 | SMN1; SMN2 (0.31) | SMN1; SMN2ADH1BADH1CADH1ATSHR | |
| SCHEMBL837941 | 0.78 | MGAM (0.42) | SMN1; SMN2ADH1BADH1CADH1AHCAR2 | |
| SCHEMBL5638650 | 0.77 | — | — | |
| SCHEMBL3498479 | 0.77 | — | — | |
| SCHEMBL8377024 | 0.77 | — | — | |
| SCHEMBL14202918 | 0.77 | POLB (0.35) | ADH1BADH1AKMT2ATSHRCA1 | |
| SCHEMBL10912548 | 0.75 | SMN1; SMN2 (0.37) | SMN1; SMN2ADH1BADH1CADH1AKMT2A | |
| SCHEMBL8610890 | 0.73 | CA14 (0.52) | SMN1; SMN2ADH1BADH1CADH1AKMT2A | |
| SCHEMBL3201079 | 0.73 | CA14 (0.52) | SMN1; SMN2ADH1BADH1CADH1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014335-A1 | PROCESS FOR PREPARATION OF PAROXETIN INTERMEDIATE | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |
| EP-0828735-A1 | PROCESS FOR PREPARING 4-ARYL-PIPERIDINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996036636-A1 | PROCESS FOR PREPARING 4-ARYL-PIPERIDINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1996-11-21 | — | — | WO | disclosed |