⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377024 | 1.00 | — | — | |
| SCHEMBL3498479 | 1.00 | — | — | |
| SCHEMBL28327470 | 0.85 | ADH1B (0.43) | — | |
| SCHEMBL26129388 | 0.85 | ADH1B (0.43) | — | |
| SCHEMBL8342022 | 0.82 | ADH1B (0.37) | — | |
| SCHEMBL23044856 | 0.81 | ADH1B (0.40) | — | |
| SCHEMBL23044829 | 0.81 | ADH1B (0.40) | — | |
| SCHEMBL11508062 | 0.80 | — | — | |
| SCHEMBL7060302 | 0.79 | MGAM (0.41) | — | |
| SCHEMBL14412682 | 0.79 | ADH1B (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021037022-A1 | METHOD FOR PREPARING 4-METHYL-5-ALKOXY OXAZOLE | 山东新和成精化科技有限公司 | 2021-03-04 | — | — | WO | claimed |
| CN-110423226-B | Preparation method of 4-methyl-5-alkoxy oxazole | 山东新和成精化科技有限公司 | 2021-01-05 | — | — | CN | claimed |
| WO-2021037022-A1 | METHOD FOR PREPARING 4-METHYL-5-ALKOXY OXAZOLE | 山东新和成精化科技有限公司 | 2021-03-04 | — | — | WO | disclosed |
| CN-110423226-B | Preparation method of 4-methyl-5-alkoxy oxazole | 山东新和成精化科技有限公司 | 2021-01-05 | — | — | CN | disclosed |
| US-20160046674-A1 | ENOPEPTINS, USES THEREOF, AND METHODS OF SNYTHESIS THEREOF | BROWN UNIVERSITY (US) | 2016-02-18 | — | — | US | disclosed |
| US-20160046674-A1 | ENOPEPTINS, USES THEREOF, AND METHODS OF SNYTHESIS THEREOF | BROWN UNIVERSITY (US) | 2016-02-18 | — | — | US | disclosed |
| US-9193767-B2 | Enopeptins, uses thereof, and methods of synthesis thereto | BROWN UNIVERSITY (US) | 2015-11-24 | — | — | US | disclosed |
| US-9193767-B2 | Enopeptins, uses thereof, and methods of synthesis thereto | BROWN UNIVERSITY (US) | 2015-11-24 | — | — | US | disclosed |
| US-20140088303-A1 | PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | SEKISUI MEDICAL CO., LTD. (JP) | 2014-03-27 | — | — | US | disclosed |
| US-8624024-B2 | Phosphoramide compound, method for producing the same, ligand, complex, catalyst and method for producing optically active alcohol | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-01-07 | — | — | US | disclosed |
| US-20120214988-A1 | PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | SEKISUI MEDICAL CO., LTD. (JP) | 2012-08-23 | — | — | US | disclosed |
| US-7220856-B2 | Substituted quinoline CCR5 receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |
| EP-1534681-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-01 | — | — | EP | disclosed |
| US-20040072818-A1 | Substituted quinoline CCR5 receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-04-15 | — | — | US | disclosed |
| WO-2004002960-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-01-08 | — | — | WO | disclosed |
| CN-1039026-A | The method for preparing trinucleated 3-oxo-propanenitrile derivatives | ERBA CARLO SPA (IT) | 1990-01-24 | — | — | CN | disclosed |