Methylene Chloride

Methylene Chloride

SCHEMBL7983107

Cc1cc(C)cc(C)c1.ClCCl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
TSHR P16473 3/20 0.50
ACHE P22303 3/20 0.41
TPMT P51580 1/20 0.38
SELL P14151 1/20 0.37
SELP P16109 1/20 0.37
SELE P16581 1/20 0.37
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
C1S P09871 1/20 0.36
PRSS3 P35030 1/20 0.36
RAPGEF4 Q8WZA2 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
HSP90AA1 P07900 1/20 0.33
CCR6 P51684 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26115 0.82
SCHEMBL341533 0.82 ALDH1A1 (0.67) ALDH1A1TSHRACHETPMTSELL
SCHEMBL1097510 0.79 ALDH1A1 (0.40) ALDH1A1TSHRACHETPMTPRSS1
SCHEMBL1043692 0.77 ALDH1A1 (0.38) ALDH1A1TSHRACHETPMTMAPK1
SCHEMBL23202757 0.77 ALDH1A1 (0.61) ALDH1A1TSHRACHETPMTSELL
SCHEMBL23202758 0.77 ALDH1A1 (0.61) ALDH1A1TSHRACHETPMTSELL
SCHEMBL432597 0.77 ALDH1A1 (0.61) ALDH1A1TSHRACHETPMTSELL
SCHEMBL25401798 0.77 ALDH1A1 (0.61) ALDH1A1TSHRACHETPMTSELL
Hydrochloric Acid SCHEMBL2443762 0.77 ALDH1A1 (0.61) ALDH1A1TSHRACHETPMTSELL
SCHEMBL1508331 0.77 ALDH1A1 (0.61) ALDH1A1TSHRACHETPMTSELL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311835-A Process for epoxidizing tetra-substituted olefins 巴斯夫农业公司 2019-02-05 CN disclosed
WO-2001016260-A1 OLIGOMERIC POLYKETONES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2001-03-08 WO disclosed