SCHEMBL7983176

SCHEMBL7983176

CCCCS(=O)(=O)N[C@H](CN(C(C)=O)N1C(=O)N[C@](C)(c2ccc(C(=N)N)cc2)C1=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 14/20 0.44
ITGA2B P08514 12/20 0.44
MRGPRX1 Q96LB2 3/20 0.36
ITGAV P06756 3/20 0.36
F10 P00742 1/20 0.33
PLG P00747 1/20 0.33
KLKB1 P03952 1/20 0.33
PROC P04070 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7443855 0.86 ITGB3 (0.36) ITGB3ITGA2BITGAV
SCHEMBL7969566 0.85 ITGB3 (0.44) ITGB3ITGA2B
SCHEMBL7982793 0.85 ITGB3 (0.43) ITGB3ITGA2BMRGPRX1ITGAVF10
SCHEMBL7443843 0.80 ITGB3 (0.53) ITGB3ITGA2BITGAV
SCHEMBL7983182 0.80 ITGB3 (0.53) ITGB3ITGA2BITGAV
Hydrochloric Acid SCHEMBL7983746 0.80 ITGB3 (0.44) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7983739 0.80 ITGB3 (0.44) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7982921 0.80 ITGB3 (0.44) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7982927 0.80 ITGB3 (0.44) ITGB3ITGA2B
SCHEMBL7983187 0.77 ITGB3 (0.44) ITGB3ITGA2BITGAVF10PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6191282-B1 DERIVATIVES OF 5-MEMBERED NITROGEN CONTAINING HETEROCYCLIC RING IS USED AS ANTICARCINOGENIC AGENT AND ANTICOAGULANT HOECHST MARION ROUSSEL (DE) 2001-02-20 US disclosed