Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684112 | 0.94 | HRH4 (0.37) | HRH4MEN1KMT2APABPC1HRH3 | |
| SCHEMBL7262300 | 0.94 | HRH4 (0.37) | HRH4MEN1KMT2APABPC1HRH3 | |
| SCHEMBL7678626 | 0.89 | TDP1 (0.39) | IMPDH2KCNJ11KDM4EMAPT | |
| SCHEMBL7261280 | 0.89 | TDP1 (0.39) | IMPDH2KCNJ11KDM4EMAPT | |
| SCHEMBL504462 | 0.87 | KCNJ11 (0.50) | IMPDH2KCNJ11 | |
| SCHEMBL504463 | 0.87 | KCNJ11 (0.50) | IMPDH2KCNJ11 | |
| SCHEMBL6954707 | 0.77 | MPI (0.37) | MEN1KMT2APABPC1IMPDH2KCNJ11 | |
| SCHEMBL6954705 | 0.77 | MPI (0.37) | MEN1KMT2APABPC1IMPDH2KCNJ11 | |
| SCHEMBL504413 | 0.77 | ALDH1A1 (0.46) | HRH4MEN1KMT2AIMPDH2KCNJ11 | |
| SCHEMBL505066 | 0.77 | ALDH1A1 (0.46) | HRH4MEN1KMT2AIMPDH2KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300345-B1 | AS ANTIPROLIFERATIVE AGENT | Leo Pharmacuetical Products Ltd. A/S (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-10-09 | — | — | US | disclosed |