Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967369 | 0.91 | ADRB3 (0.55) | ADRB3ADRA1A | |
| SCHEMBL7980858 | 0.91 | ADRB3 (0.55) | ADRB3ADRA1A | |
| SCHEMBL7967364 | 0.91 | ADRB3 (0.55) | ADRB3ADRA1A | |
| Hydrochloric Acid SCHEMBL7984010 | 0.90 | ADRB3 (0.54) | ADRB3ADRA1A | |
| Hydrochloric Acid SCHEMBL7984008 | 0.90 | ADRB3 (0.54) | ADRB3ADRA1A | |
| SCHEMBL7977126 | 0.90 | ADRB3 (0.46) | ADRB3ADRA1A | |
| SCHEMBL7967611 | 0.87 | ADRB3 (0.62) | ADRB3ADRA1ADRD2DRD3DRD4 | |
| SCHEMBL7978980 | 0.87 | ADRB3 (0.62) | ADRB3ADRA1ADRD2DRD3DRD4 | |
| SCHEMBL6915256 | 0.86 | ADRB3 (0.53) | ADRB3ADRA1ADRD2DRD3DRD4 | |
| SCHEMBL5195913 | 0.86 | ADRB3 (0.51) | ADRB3ADRA1ADRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | claimed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | claimed |
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |