Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.59 |
| ▸ | CA1 | P00915 | 8/20 | 0.59 |
| ▸ | CA9 | Q16790 | 8/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113710 | 0.83 | TSHR (0.61) | CA2CA1CA9TSHRCA5A | |
| SCHEMBL1621831 | 0.80 | CA2 (0.55) | CA2CA1CA9TSHRCA5A | |
| SCHEMBL16657622 | 0.79 | TSHR (0.56) | CA2CA1CA9TSHRCA5A | |
| SCHEMBL15186464 | 0.78 | TSHR (0.54) | CA2CA1CA9TSHRCA5A | |
| SCHEMBL23461748 | 0.77 | CA2 (0.52) | CA2CA1CA9TSHRCA5A | |
| SCHEMBL1002697 | 0.77 | CA2 (0.52) | CA2CA1CA9TSHRCA5A | |
| Sulfuric Acid SCHEMBL21681660 | 0.76 | TSHR (0.71) | CA2CA1CA9TSHRCA12 | |
| SCHEMBL9451226 | 0.75 | CA2 (0.69) | CA2CA1CA9TSHRCA5A | |
| SCHEMBL22071071 | 0.74 | CA2 (0.49) | CA2CA1CA9TSHRCA5A | |
| Sulfuric Acid SCHEMBL11103729 | 0.74 | TSHR (0.68) | CA2CA1CA9TSHRCA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081322-A1 | NON-IMIDAZOLE BENZODIAZEPINE INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-01 | — | — | WO | disclosed |