Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987519 | 0.97 | PRKAA2 (0.44) | DRD4PRKAA2HTR2AKDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL7972057 | 0.97 | PRKAA2 (0.44) | DRD4PRKAA2HTR2AKDM4ECYP1A2 | |
| SCHEMBL7971755 | 0.93 | DRD4 (0.53) | DRD4PRKAA2HTR2AKDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL7983770 | 0.92 | DRD4 (0.52) | DRD4PRKAA2HTR2AKDM4ECYP1A2 | |
| SCHEMBL7971899 | 0.90 | DRD4 (0.52) | DRD4PRKAA2KDM4ESIGMAR1ADRA1D | |
| Hydrochloric Acid SCHEMBL7982255 | 0.89 | DRD4 (0.44) | DRD4PRKAA2HTR2ASIGMAR1ADRA1D | |
| Hydrochloric Acid SCHEMBL7971892 | 0.89 | DRD4 (0.52) | DRD4PRKAA2KDM4ESIGMAR1ADRA1D | |
| SCHEMBL7973256 | 0.87 | PRKAA2 (0.47) | DRD4PRKAA2HTR2AHTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL7972396 | 0.86 | PRKAA2 (0.46) | DRD4PRKAA2HTR2AHTR1ADRD3 | |
| SCHEMBL7983507 | 0.86 | DRD4 (0.51) | DRD4PRKAA2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |