Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972057 | 0.99 | PRKAA2 (0.44) | PRKAA2DRD4MCHR1SIGMAR1SLC6A12 | |
| SCHEMBL7983602 | 0.97 | DRD4 (0.45) | PRKAA2DRD4MCHR1SIGMAR1SLC6A12 | |
| SCHEMBL7971899 | 0.92 | DRD4 (0.52) | PRKAA2DRD4SIGMAR1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7982255 | 0.92 | DRD4 (0.44) | PRKAA2DRD4SIGMAR1HTR2AADRA1D | |
| Hydrochloric Acid SCHEMBL7971892 | 0.92 | DRD4 (0.52) | PRKAA2DRD4SIGMAR1ADRA1DADRA1A | |
| SCHEMBL7971755 | 0.90 | DRD4 (0.53) | PRKAA2DRD4SIGMAR1HTR2AADRA1D | |
| SCHEMBL7973256 | 0.90 | PRKAA2 (0.47) | PRKAA2DRD4DRD3HTR2ACACNA1F | |
| Hydrochloric Acid SCHEMBL7983770 | 0.89 | DRD4 (0.52) | PRKAA2DRD4SIGMAR1HTR2AADRA1D | |
| Hydrochloric Acid SCHEMBL7972396 | 0.89 | PRKAA2 (0.46) | PRKAA2DRD4DRD3HTR2ACACNA1F | |
| SCHEMBL7989275 | 0.89 | CCR3 (0.47) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |