Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983641 | 0.75 | HTR2C (0.63) | HTR2CHTR2AHTR2B | |
| SCHEMBL7983649 | 0.75 | HTR2C (0.63) | HTR2CHTR2AHTR2B | |
| SCHEMBL7997598 | 0.68 | HTR2C (0.81) | HTR2CHTR2AHTR2B | |
| SCHEMBL7093740 | 0.68 | HTR2C (0.81) | HTR2CHTR2AHTR2B | |
| SCHEMBL24109929 | 0.66 | HTR2C (0.62) | HTR2CHTR2AHTR7MTNR1AMTNR1B | |
| SCHEMBL7995774 | 0.66 | HTR2C (0.56) | HTR2CHTR2AHTR2B | |
| SCHEMBL24110213 | 0.64 | HTR2C (0.60) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL18997057 | 0.64 | HTR2C (0.59) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL980885 | 0.64 | HTR2C (0.65) | HTR2CHTR2AHTR7MTNR1AMTNR1B | |
| SCHEMBL13662241 | 0.63 | HTR2C (0.65) | HTR2CHTR2AHTR7MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | claimed |